Erythropoietin (EPO) is a glycoprotein hormone produced in the kidney. EPO promotes red blood cell production. A single gene located in chromosome 7 regulates the production of erythropoietin, which primarily takes place in the kidneys. Approximately 10% of erythropoietin is synthesized in the liver and other extra-renal organs.

Diagram displaying the EPO gene with a variety of features displayed including the peptides, glycosylation sites, SCOP domains, disorder, hydropathy, exon structure, homology models of EPO