F-actin F actin is the filamentous form of actin, the most abundant protein in most eukaryotic cells. Actin participates in more protein-protein interactions than any known protein and it is a critical player in many cellular functions, such as cell motility, maintenance of cell shape and polarity, or regulation of transcription.
F-actin F actin, for example, plays a core role in muscle contraction because of its interaction with myosin in muscle cells.
F-actin conformation also depends on the type of cell they are expressed. For instance, F-actin distribution in epithelial cells F actin conformation also depends on the type of cell they are expressed. For instance, F actin distribution in epithelial cells can be detected predominantly on the edges when visualizing them under a fluorescence microscope using fluorescence-labeled antibodies to tag the protein.
Due to its central role in the cell, mutations or changes in F-actin F actin expression are linked to different biological processes, like the Epithelial-Mesenchymal transition (EMT), or to diseases, especially muscular ones.