Fibroblast cell

A fibroblast cell is a type of cell that synthesizes the extracellular matrix and collagen, the structural framework for animal tissues. They also play a critical role in wound healing. Following tissue injury, fibroblasts migrate to the damaged site, where they deposit new collagen and facilitate the healing process. Fibroblasts are derived from the mesenchyme. Fibroblast cells have an elongated flattened, oblong or triangular form. Fibroblast cells also have branched cytoplasm surrounding an elliptical nucleus with 1 or 2 nucleoli.

A sample of fibroblast cells seen through the microscope. These cells are thin and elongated, with a spindle-like shape. They have small nuclei and a small amount of cytoplasm relative to their size. The cell confluence in this image is about 90%.

Figure 1: Fibroblast cells