Hematology analyzers are used in medical laboratories to automatically generate complete blood counts (Figure 1). After the sample is injected, it is mixed with an electrolyte solution. The electrolyte solution is conductive while blood cells are non-conductive. This enables the determination of the total cell count based on the increase in electrical resistance, also called impedance when the cells pass through an electrical field (Figure 2).

Figure 1: Automatic hematology analyzer.

Figure 2: Schematic representation of cell counting in a hematology analyzer based on electrical impedance.