Organometallic reagents are chemical compounds that contain carbon-metal bonds. When the metal involved is Lithium we can also refer to it as an organolithium reagent; when the metal is Magnesium they are known as Grignard reagents.

Organometallic reagents provide a source of highly nucleophilic carbon which makes them great starting materials in organic chemistry. They are one of the most synthetically useful reagents for installing new carbon-carbon bonds.