Rad52

Rad52 protein in Sacchromyces cerevisae plays an important role in double-strand break repair by homologous recombination. Rad52 forms heptameric ring that catalyses DNA annealing and mediates Rad51-mediated strand invasion. Rad52 protein also protect 3' single-stranded DNA from exonucleolytic digestion in homologous recombination process.