Ring-straight chain isomerism
Monosaccharides can exist as a linear chain or as a ring-shaped molecule; in aqueous solutions they are usually found in the ring form. When Glucose is present in a ring form it can have two different arrangements of the hydroxyl group (OH) around the anomeric carbon (carbon 1 that becomes asymmetric in the process of ring formation). If the hydroxyl group is below the plane of carbon 1 in the sugar, it is said to be in the alpha (α) position, and if it is above the plane, it is said to be in the beta (β) position.
Figure 1: Conversion between linear and ring forms of glucose.
Five-membered rings can also be formed.