Sensory transduction: Learn why you feel pain when you get hit by a rock

Welcome to the Sensory Transduction simulation. In this simulation, you will learn about how different stimuli result in a range of sensations. You will use a voltage-patch clamp to experiment directly on sensory neurons and live animal testing to determine the mechanism of action of two drugs that inhibit pain.

The following is a list of the relevant theory pages:

• Sensory Neurons

  • Mechanoreceptors
  • Thermoreceptors
  • Chemoreceptors
  • Photoreceptors
  • Nociceptors
    • Capsaicin

• Action Potential

  • Ion channels
    • Voltage-gated ion channels
      • Voltage-gated sodium channels
      • Voltage-gated potassium channel
    • TRPV1 channel
  • Channel Blockers

• Patch Clamp Experiments

  • Voltage Clamp Method
  • Current Clamp Method

• Latency to Withdrawal

• Lidocaine