Perform a Dry Western Blot

In this simulation, you will learn how tumor cells send signals to surrounding cells to help promote tumor growth, and how this signal is transferred inside the cell. As a researcher in the R&D department of a big pharmaceutical company, your mission is to test different inhibitors targeting a specific class of signaling receptors (receptor tyrosine kinases). Will you be able to identify a promising new drug candidate for treating patients with breast cancer?

You will be able to find all the related theory needed to complete the course in this theory page.

Good luck and have fun!

• Angiogenesis
  • Angiogenesis and Cancer
• Cell Membrane
• Signal Transduction
  • Cell-Surface Receptor
  • Signaling Cascade
• Receptor Tyrosine Kinase (RTK)
  • Vascular Endothelial Growth Factor (VEGF)
  • Vascular Endothelial Growth Factor Receptor (VEGFR)
• Protein Phosphorylation

Techniques

• Western Blot
  • Gel Electrophoresis
  • Antibodies Used in Western Blotting
• Mouse Model

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Acknowledgement The content of these theory pages has been developed based on the resources provided by:

• OpenStax College, Biology. (OpenStax CNX. Mar 13, 2015)