Nucleophilic Addition: Explore the Grignard Reaction

In this simulation, you will learn about the nucleophilic addition reaction and one of the most synthetically useful types of nucleophilic addition reaction - the Grignard reaction!

Remember that you can access the theory section at any time from your LabPad while playing the simulation.

Below is a list of all the relevant theory pages to help boost your learning:

• Overview of common functional groups

• Nucleophilic Addition Reaction

  • Reaction Terminology

  • Electrophile

  • Nucleophile

  • Formal charge

  • Steric hindrance

  • Selectivity in asymmetric addition reactions

• The Grignard Reaction

  • Organometallic reagents

• Drug discovery

  • Pharmaceutical scale-up

  • Tamoxifen

• Draw reaction mechanisms

• Regioselectivity

• Stereochemistry